drug safety assessment
with regard to human microbiota


It is important to understand exactly what harms beneficial bacteria. For example, whether a medicine kills them - or their drug-sensitive "allies"

It is important to understand exactly what harms beneficial bacteria. For example, whether a medicine kills them - or their drug-sensitive "allies"

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drugs can also
harm

Antibiotics and other medical drugs not only help us fight against infections, but also disrupt our microbial communities. On the other hand, the microbes can change the way drugs act on our health. Knomics helps to untangle the complex net of interactions between bacteria and medical compounds.

Antibiotics and other medical drugs not only help us fight against infections, but also disrupt our microbial communities. On the other hand, the microbes can change the way drugs act on our health. Knomics helps to untangle the complex net of interactions between bacteria and medical compounds.

so what this is
all for?

We conduct additional clinical trials examining microbiota-mediated effects of drugs on human health
Aid in development of improved medical preparations with reduced negative effects on microbiota
Shield
We conduct additional clinical trials examining microbiota-mediated effects of drugs on human health
Aid in development of improved medical preparations with reduced negative effects on microbiota
Shield

how it all
works

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we collect the samples

Microbiota samples are collected
from patients before and after
the drug therapy.

Microbiota samples are collected from patients before and after the drug therapy.

how it all
works

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we analyse samples in the lab

Metagenomic sequencing allows
precise identification of changes
in microbial community structure
caused by the treatment.

Metagenomic sequencing allows precise identification of changes in microbial community structure caused by the treatment.

how it all
works

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less damage, better drugs

Understanding of specific effects
of a drug on microbiota allows to
introduce components helping to reduce
collateral damage of a drug on our
beneficial microbes.

Understanding of specific effects of a drug on microbiota allows to introduce components helping to reduce collateral damage of a drug on our beneficial microbes.